Although the polymerase chain reaction has revolutionized genetic analysis by amplifying rare nucleic acid sequences, the in situ application is the only method that allows the localization of amplified signal within tissue structure. The applications of in situ polymerase chain reaction have greatly enhanced the field of investigation in many disciplines, including viral infections, gene modification, tumor diagnosis, gene therapy, and cellular... more...

Solid state Nmr is rapidly emerging as a universally applicable method for the characterization of ordered structures that cannot be studied with solution methods or diffraction techniques. This proceedings -; from a recent international workshop - captures an image of the latest developments and future directions for solid state Nmr in biological research, particularly on membrane proteins. Detailed information on how hormones or drugs bind to their... more...

This Atlas attempts to dispel some of the mystery surrounding stomatocysts, to facilitate the accurate identification of individual cyst morphotypes, and to encourage other workers to begin using these important indicators of environmental change. The terminology is outlined in detail. This is followed by detailed descriptions of cyst morphotypes, which continues from work completed in the first Atlas. Any available biogeographical and ecological... more...

The Who's Who in Fluorescence 2003 volume was published in November 2002. It featured some 312 personal entries from fluorescence workers all over the world. Initially we were unsure how useful the volume would be. However, it wasn't very long before we were inundated with requests for both bulk and personal orders. In addition a significant number of copies were freely distributed at conference venues, such as at the Biophysical Society meeting in San... more...

In a clear exposition this inspirational book shows the in situ three-dimensional morphology of cerebellar neurons, intracortical circuits and synaptic connections that underpin the functioning of cerebellar neurons in networks. It brings together in one volume a new view of the three-dimensional cytoarchitectonic arrangement of the cerebellar cortex. The book shows the cerebellar extrinsic and intrinsic intracortical circuits formed... more...

Since antibodies tagged with markers have been developed, immunocytochemistry has become an important method for identifying tissue substances and the localisation of nucleic acid in tissue by in situ hybridisation in molecular biology. This laboratory book covers the embedding of tissue using less sensitive epoxy resin methods to the more sensitive procedures employing the acrylics. The possibilities are discussed and results are presented so that an... more...

Reviews in Fluorescence 2004, the first book of a new book series from Springer, is a collection of current trends and emerging hot topics in the field of Fluorescence. This annual review series differs from Springer's current Topics in Fluorescence series in that it is more specialized and includes reviews of an individual's own work or scientific perspective. Reviews in Fluorescence will therefore complement the other fluorescence... more...

The Journal of Fluorescence’s fourth Who’s Who directory is to publish the names, contact details, specialty keywords, and a brief description of scientists employing fluorescence methodology and instrumentation in their working lives. In addition, the directory will provide company contact details with a brief list of fluorescence-related products. The directory will be edited by Chris D. Geddes and Joseph R. Lakowicz, editor and... more...

This is the third volume in the Reviews in Fluorescence series. To date, two volumes have been both published and well received by the scientific community. Several book reviews have also favorably described the series as an "excellent compilation of material which is well balanced from authors in both the US and Europe". Of particular mention we note the recent book review in JACS by Gary Baker, Los Alamos. In this 3rd volume we continue the tradition... more...

This collection of papers written by leading researchers reflects the forefront of research in the dynamic field of quantum optics. Topics covered include BEC, atomic optics, quantum information, cavity QED and quantum noise processes. This volume forms an indispensable reference source for all those who want to keep up with the latest developments in this area.