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Showing: 1-10 results of 3344

This book provides an introductory text for undergraduate and graduate students who are interested in comprehensive biological systems. The authors offer a broad overview of the field using key examples and typical approaches to experimental design. The volume begins with an introduction to systems biology and then details experimental omics tools. Other sections introduce the reader to challenging computational approaches. The final... more...

Regulation of Gene Expression: Molecular Mechanisms presents a comprehensive overview of methods and approaches for characterizing mechanisms of gene regulation. The text is appropriate both as a graduate textbook and a standard laboratory reference and provides the essential groundwork for an advanced understanding of the various mechanisms that may result in altered activity of a specific cell protein. Each of three sections explores mechanisms of... more...

Contents S. Rospert, M. Rakwalska and Y. Dubaquie Polypeptide chain termination and stop codon readthrough on eukaryotic ribosomes A.S. Verkman Novel roles of aquaporins revealed by phenotype analysis of knockout mice M.J. Cismowski and S.M. Lanier Activation of heterotrimeric G-proteins independent of a G-protein coupled receptor and the implications for signal processing

A great deal of confusion and uncertainty over genotoxic impurity (GTI) identification, assessment, and control exists in the pharmaceutical industry today. Pharmaceutical Industry Practices on Genotoxic Impurities strives to facilitate scientific and systematic consensus on GTI management by presenting rationales, strategies, methods, interpretations, practices, and case studies from the pharmaceutical industry. Featuring the... more...

Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for biopharmaceutical researchers and others in the health sciences community, it provides an up-to-date volume on conceptual and analytical... more...


Effective Techniques for Manipulating, Persuading, & Influencing People! All of us have experienced manipulation in some form or another in our lives. It can present itself in the form of a commercial on television, a billboard ad on the street, or a sales person that is trying to convince you to purchase a product or service. It can commonly be experienced in your social or personal relationships such as your friend asking you... more...

This book examines insights into the latest thinking and core concepts in areas of key methodological endeavor in Pharmacovigilance (PV), which strives to ever more effectively protect patients from harm caused by the medicines they need. Each book chapter tends to have a clear quantitative or clinical slant and an aim to provide an overview of methodological insights within a specific topic, while also providing a perspective on how the area is... more...

Presents the latest research and applications for a new, promising approach to fighting infectious diseasesEnzybiotics is a promising way of fighting bacterial or fungal infectious diseases by using viruses or viral-derived lysins. Drawing from the fields of medicinal chemistry, microbiology, genetics, and biochemistry, this book presents the state of the science in enzybiotics research, fully exploring its emerging therapeutic applications.The book... more...

Relied upon by dermatologists and medical practitioners internationally for its unparalleled practical focus on adverse effects and cutaneous reactions, this text is the essential quick-reference tool for patient care and drug safety. The reaction data for this new 20th edition is compiled from the companion website, which is updated continuously, and includes prescription and over-the-counter drugs as well as biologics,... more...

This comprehensive review provides a systematic, unbiased analysis, critique and summary of the available literature and generates novel clinical decision-making algorithms which can aid clinicians and scientists in practice management and research development. Potential mechanisms for the identified drug interactions are deduced from available preclinical and in vitro data which are interpreted in the context of the in vivo findings.... more...