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Showing: 1-10 results of 2922


Due to recent advances in laparoscopic gastrectomy for gastric cancer, a high-resolution atlas in this field was felt necessary. This book describes the laparoscopic surgical procedure and precautions of lymph node (LN) dissection, comprehensively. The details of preoperative preparation, regional LN dissection, and digestive tract reconstruction are introduced based on a large numbers of clinical cases. Modified intracorporeal anastomosis... more...

Each volume provides the reader, whether engaged in chemistry, biochemistry, biology or molecular medicine, with a comprehensive summary and critical overview of a topic of great current interest written by leading international experts.

This text provides a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for clinicians, pathologists and researchers with an interest in GVHD and its mimickers. The book reviews new data about risk factors affecting outcomes, pathologic features, and profiles the new WHO guidelines as well as current practices. The richly illustrated text covers the gamut of gross and histologic presentations of... more...

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Oncology in Primary Care is for primary care clinicians who need practical and concise information on caring for their patients with cancer. Written in an easy-to-browse format, chapters cover risk factors,... more...


This book is the first one written about the JAK/STAT pathway. The JAK (Janus Kinase) Protein tyrosine kinases are novel phosphotransferases absolutely required for cellular signalling downstream of non-catalytic cytokine receptors (amongst others). These molecules are components in pathways utilising the STAT (Signal Transducers and Activators of Transcription) transcription factors. The basic components of the JAK/STAT pathway are covered in detail,... more...

Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research and with exciting potential clinical applications. The... more...

Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first... more...

The series, Hormones in Health and Disease, was launched in 1993 to provide a scientific platform for investigators engaged in research on the biological actions of hormones and to anticipate relevance for their findings in clinical applications. The first volume of the series was dedicated to the discussion and understanding of molecular mechanisms by which steroid hormones influence target cells in normal and pathological conditions. With the... more...

The contribution of epithelia-mesenchyme interaction to normal development (eg., tissue formation) and to neoplasia has become a subject of increasing interest to scientists because of recent progress in deciphering the molecular signals that mediate this interaction. Clearly, some of the same types of molecules (eg., growth factors and their receptors, proteolytic enzymes, cell adhesion molecules, and structural proteins of the extracellular matrix)... more...