This comprehensive atlas is unique in being devoted to the MRI
appearances of bone marrow in the axial and appendicular skeleton
of adults and children. Normal MRI findings, including common
variants and degenerative changes, are first documented. MRI
appearances in the entire spectrum of neoplastic and
non-neoplastic infiltrative marrow disorders are then presented,
with accompanying explanatory text. Among the conditions
This is a timely compilation of new concepts in the molecular
pathogenesis and molecular therapy of acute myelogenous leukemia
(AML). The focus is on selected critical molecular determinants
of AML pathogenesis and pathophysiology and the exploitation of
these factors by diverse therapeutic agents and modalities. There
is an emphasis throughout on the bidirectional flow of knowledge
between the clinical and laboratory arenas.
...includes new information on molecular biology, bone marrow stem
cell transplantation, markers for thrombosis, and new learning aids
including chapter objectives, more case studies, color plates,
chapter review questions, etc.
Emerging technologies in target identification, drug discovery,
molecular markers, and imaging are rapidly changing the face of
cancer. This book provides a foundation of knowledge in targeted
cancer therapeutics. The treatment of cancer is increasingly
being individualized, based on an understanding of underlying
biologic mechanisms. Poised to change the landscape in oncology,
this volume provides a state-of-the-art overview. It will... more...
The dogmas of the quiet past are inadequate to the stormy present.
The occasion is piled high with difficulty, and we must rise with
the occasion. As our case is new, so we must think anew and act
anew. Abraham Lincoln, 1862 When I came across this quote, it made
me recall my first participation at an international meeting on
bone marrow transplantation, at a time when this was the only term
that was used to describe the field. During a particular... more...
In this book, a group of internationally distinguished lymphoma
experts provide a comprehensive review of the most important
advances in the biology, diagnosis, and therapy of T cell and NK
cell malignancies. In particular, it demonstrates in detail how
advances in our understanding of the tumor microenvironment and
molecular biology have helped to elucidate the pathogenesis of
these lymphomas, improve diagnostic and prognostic accuracy,... more...
This book provides a detailed review of the most recent
pathogenetic, diagnostic and therapeutic approaches in connection
with Helicobacter pylori, along with priority areas in research and
trends in clinical practice to address this significant pathogen
acknowledged as the causative agent in a wide range of diseases,
including gastric adenocarcinoma, MALT lymphoma and immune
thrombocytopenic purpura (ITP). Medical authorities worldwide now
recommend a... more...
A cross between a dictionary and an encyclopedia, Desk Reference
for Hematology, Second Edition presents a concise yet thorough
examination of hematology and its relationship with other systems
and disorders. The 1500 alphabetically listed articles provide
quick and easy access to expert information, the 150 tables put
precise data at your fingertips, and the 100 figures are a visual
tool that clarify the text. The book also includes 500 references
Clinical Hepatology – Principles and Practice of Hepatobiliary
Diseases provides clear and comprehensive coverage of the
etiology, mechanisms of disease, diagnosis, and practical
management of the entire spectrum of liver and biliary disorders.
It also affords an excellent, evidence-based review of the
rapidly expanding field of hepatobiliary diseases.
This book elucidates a number of new concepts on P-wave evaluation
and QRS depolarization properties, and reports on several
repolarization findings never covered in previous ECG books. The
content is primarily based on case reports, some of which are
compared in order to reveal their ostensibly small but significant
differences. The book addresses a significant and lingering gap in
ECG interpretation, which is the actual cause of many poor