This volume provides a comprehensive overview of critical care of
the pediatric immunocompromised hematology-oncology patient. The
text focuses on unique aspects of the pediatric immunocompromised
patient that predisposes the child to significant illness, and
presents critical care management strategies specific to the
patient population. In addition to chapters on oncology, primary
immune deficiency, immunocompromised hematology, and... more...
The use of Epo in medical practice is increasing constantly. It has
revolutionized how we think of blood transfusion in medicine and
surgery. Moreover, it has become widely known to scientists,
physicians, biotech and pharmaceutical executives and the general
public. Additionally, the past ten years have seen important
advances in our knowledge and understanding of its action both
within and outside of the hematopoietic system.
Until now, there has... more...
As haemophilia is a life-long condition, continuing supervision by
a group of medical personnel is required. In many countries this is
provided by comprehensive care haemophilia centres where staff of
all specialities concerned with treatment- haematologists,
paediatricians, nurses, physiotherapists, orthopaedic surgeons -
have specialized knowledge.
This new book is a definitive resource on the current aspects and
issues around haemophilia.... more...
...includes new information on molecular biology, bone marrow stem
cell transplantation, markers for thrombosis, and new learning aids
including chapter objectives, more case studies, color plates,
chapter review questions, etc.
Emerging technologies in target identification, drug discovery,
molecular markers, and imaging are rapidly changing the face of
cancer. This book provides a foundation of knowledge in targeted
cancer therapeutics. The treatment of cancer is increasingly
being individualized, based on an understanding of underlying
biologic mechanisms. Poised to change the landscape in oncology,
this volume provides a state-of-the-art overview. It will... more...
The dogmas of the quiet past are inadequate to the stormy present.
The occasion is piled high with difficulty, and we must rise with
the occasion. As our case is new, so we must think anew and act
anew. Abraham Lincoln, 1862 When I came across this quote, it made
me recall my first participation at an international meeting on
bone marrow transplantation, at a time when this was the only term
that was used to describe the field. During a particular... more...
This is a timely compilation of new concepts in the molecular
pathogenesis and molecular therapy of acute myelogenous leukemia
(AML). The focus is on selected critical molecular determinants
of AML pathogenesis and pathophysiology and the exploitation of
these factors by diverse therapeutic agents and modalities. There
is an emphasis throughout on the bidirectional flow of knowledge
between the clinical and laboratory arenas.
Pulmonary embolism is a common but vexing illness. This book
provides a contemporary overview of the most important issues from
a Western and a Japanese perspective, providing the reader with
state-of-the-art knowledge of the epidemiology and molecular
biology of the disease. In the Diagnosis section, the relationship
between venous thrombosis and pulmonary embolism is explored, and
exciting new findings are presented in the fields of
In this book, a group of internationally distinguished lymphoma
experts provide a comprehensive review of the most important
advances in the biology, diagnosis, and therapy of T cell and NK
cell malignancies. In particular, it demonstrates in detail how
advances in our understanding of the tumor microenvironment and
molecular biology have helped to elucidate the pathogenesis of
these lymphomas, improve diagnostic and prognostic accuracy,... more...
This book summarizes current knowledge of the biology and
molecular pathogenesis of aggressive lymphomas and reviews the
state of the art in diagnostic and therapeutic strategies. The
aim is both to provide the reader with a sound understanding of
the very significant progress that has been achieved in the
understanding and management of these malignancies over recent
years and to facilitate appropriate choice of the therapeutic... more...