Whenever the heart is challenged with an increased work load for a
prolonged period, it responds by increasing its muscle mass--a
phenomenon known as cardiac hypertrophy. Although cardiac
hypertrophy is commonly seen under physiological conditions such as
development and exercise, a wide variety of pathological situa
tions such as hypertension (pressure overload), valvular defects
(volume overload), myocardial infarction (muscle loss), and... more...