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An Introduction to Human Disease: Pathology and Pathophysiology Correlations, Ninth Edition provides students with a clear and well-illustrated explanation of the structural and functional changes associated with disease, the clinical manifestations of disease, and how to determine treatment. Ideal for Pathology, Pathophysiology, or Human Disease courses, the first part of the text deals with general concepts and with diseases affecting the body as a... more...

Richard A. Prayson, md, summarizes in outline form for active pathologists and residents in training-as well as those seeking a concise up-to-date overview of the subject -the essential element of the neuropathology curriculum. Topics range from basic information on the spectrum of neurologic-related disease to pertinent pictorial examples of many neuropathologic conditions. For each topic there are self-assessment tests based on both textual and... more...

This book had its genesIs In the frustrations of the editors in locating authoritative, up-to-date material for an interdisciplinary graduate course in mammary gland biology, lactation, and breast-feeding. As we turned to the original literature several reasons for the dearth of usable material became clear: (1) In the areas of mammary gland biology and physiology, particularly as they relate to the human, reviews simply have not kept up with current... more...

Portable Pathophysiology is a full-color, comprehensive, carry-along, A-to-Z atlas that shows how more than 150 disorders can disrupt the human body's equilibrium. Covering every body system, the unique two-page format provides text and a physiologic changes chart on the left page and full-color Anatomical Chart Company art with callouts on the right page. Charts are used in the text to link the pathophysiology behind... more...

The human brain represents about 2% of the body weight, yet it accounts for approximately 20% of aerobic metabolism. This high dependency on energy-consuming processes is mainly caused by the active transport of ions, which is necessary to compensate for the transmembrane ion currents that are part ofthe complex signaling processes in the brain. Ninety-five percent ofthe brain's ATP is derived from mitochondrial oxidative phosphorylation. Since that... more...


The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the level of adjacent endothelial cells, which are coupled to astrocytes, microglia, neurons and pericytes. The structure of this endothelial barrier is unique among endothelia of other organ systems and is... more...

A clear, comprehensive introduction to disease, Pathophysiology, 5th Edition explores the etiology, pathogenesis, clinical manifestations, and treatment of disorders. Units are organized by body system, and each begins with an illustrated review of anatomy and normal physiology. A discussion then follows on the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by leading... more...

Healthcare professionals, including doctors, pharmacists and nurses, are often confronted with patients who use over-the-counter (OTC) herbal medicinal products and food supplements. While taking responsibility for one’s own health and treatment options is encouraged, many patients use these products based on limited (and sometimes inaccurate) information from non-scientific sources, such as the popular press and internet. There is a... more...

Easy-to-follow disorder-based organization that surveys the full range of organ system disorders treated in pharmacy practice Knowledge-building boxed features within chapters, consisting of: Clinical Presentation & Diagnosis, Patient Encounters, and Patient Care and Monitoring Guidelines A standardized chapter format Laboratory values expressed in both conventional units and Systemé International (SI) units

Rheumatoid arthritis is a crippling disease, affecting individuals in the prime of their life. This disease is emerging as a paradigm for complex autoimmune syndromes in which multiple genetic risk determinants in combination with non-inherited factors predispose individuals to generate chronically persistent and destructive immune responses. As a consequence of exploring the immunopathology of rheumatoid arthritis, biologic response modifiers have... more...