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With easy-to-read, in-depth descriptions of disease, disease etiology, and disease processes, Pathophysiology: The Biologic Basis for Disease in Adults and Children, 7th Edition helps you understand the most important and the most complex pathophysiology concepts. More than 1,200 full-color illustrations and photographs make it easier to identify normal anatomy and physiology, as well as alterations of function. This edition includes a... more...

A clear, comprehensive introduction to disease, Pathophysiology, 5th Edition explores the etiology, pathogenesis, clinical manifestations, and treatment of disorders. Units are organized by body system, and each begins with an illustrated review of anatomy and normal physiology. A discussion then follows on the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by leading... more...

This collection of articles by leading orthopedic and craniofacial surgeons and researchers comprehensively reviews the biology of bone formation and repair, the basic science of autologous bone graft, allograft, bone substitutes, and growth factors, and explore their clinical application in patients with bone repair problems.

Healthcare professionals, including doctors, pharmacists and nurses, are often confronted with patients who use over-the-counter (OTC) herbal medicinal products and food supplements. While taking responsibility for one’s own health and treatment options is encouraged, many patients use these products based on limited (and sometimes inaccurate) information from non-scientific sources, such as the popular press and internet. There is a... more...

Are free radicals and reactive oxygen species relevant to dermatopathology? Do antioxidants protect against free-radical-mediated cutaneous diseases and aging? To these and further current questions in the rapidly progressing field of basic and applied skin research, this up-to-date volume provides a scientific basis. It presents state-of-the-art reviews on the progress in detection of free radicals and antioxidants and their responses to environmental... more...


A unique system/disease-based approach to learning pulmonary pathophysiology as it relates to clinical medicine No other review puts disorders of lung structure and function in such clear clinical perspective as Pulmonary Pathophysiology. Bridging the gap between basic science and clinical medicine, Pulmonary Pathophysiology guides you from symptom identification to underlying disease mechanisms and through principles of management.... more...

The human brain represents about 2% of the body weight, yet it accounts for approximately 20% of aerobic metabolism. This high dependency on energy-consuming processes is mainly caused by the active transport of ions, which is necessary to compensate for the transmembrane ion currents that are part ofthe complex signaling processes in the brain. Ninety-five percent ofthe brain's ATP is derived from mitochondrial oxidative phosphorylation. Since that... more...

The blood-brain barrier (BBB) is a complex and dynamic structure that protects the brain from cells within the vasculature, from the immune system and from pathogens. This barrier is present in arterioles, capillaries and venules and is formed at the level of adjacent endothelial cells, which are coupled to astrocytes, microglia, neurons and pericytes. The structure of this endothelial barrier is unique among endothelia of other organ systems and is... more...

Easy-to-follow disorder-based organization that surveys the full range of organ system disorders treated in pharmacy practice Knowledge-building boxed features within chapters, consisting of: Clinical Presentation & Diagnosis, Patient Encounters, and Patient Care and Monitoring Guidelines A standardized chapter format Laboratory values expressed in both conventional units and Systemé International (SI) units

Rheumatoid arthritis is a crippling disease, affecting individuals in the prime of their life. This disease is emerging as a paradigm for complex autoimmune syndromes in which multiple genetic risk determinants in combination with non-inherited factors predispose individuals to generate chronically persistent and destructive immune responses. As a consequence of exploring the immunopathology of rheumatoid arthritis, biologic response modifiers have... more...